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Plp-creert2 mouse

Webb4 mars 2024 · However, the Plp-CreERT2 line cannot be used with confidence to assess the distribution of melanoblasts arising via ventrally migrating routes in mice. As such, further work needs to be done to dissect the lineage relationship between SCP cells and melanocytes in mice, yet a common glial–melanogenic bipotent progenitor is not in doubt. Webb4 mars 2024 · Mice expressing tamoxifen-inducible Cre Ert2 under the control of the Plp promotor (MGI:2663093) 26 were obtained from Ueli Suter, ETH Zurich Institute for …

Oligodendrocyte-Encoded HIF Function Couples Postnatal …

WebbCre-ERT2小鼠是一类含有雌激素受体（estrogen receptor，ER）的配体结合区突变体（ERT）与Cre重组酶的融合蛋白表达的小鼠。. Cre-ERT2在无Tamoxifen诱导的情况 … Webb16 okt. 2009 · We used PLP-CreERT2 mice to genetically trace the progeny of PLP + SCPs unequivocally identifying SCPs as a cellular origin of melanocytes during mouse development. This data also shows that DCT + /Mitf + mature pigmented melanocytes derived from SCPs appear at cutaneous sites in the postnatal animal. fulton county schools special needs services https://neo-performance-coaching.com

Plp Creert2 Mice Bioz Ratings For Life-Science Research

Webb4 apr. 2012 · We intercrossed Pten flox/flox mice to a TM inducible Plp-CreERT2 driver line (Leone et al, 2003). Two month-old double transgenics (Pten flox/flox *Plp-CreERT2) and Pten flox/flox controls received intraperitoneal TM injections for 10 consecutive days, and were analysed histologically 3.5 months later. Webb15 juni 2012 · In a second mouse line, inducible Plp-CreERT2 expression has been used by others to investigate a transition from SCPs to melanocytes (Leone et al., 2003; Adameyko et al., 2009). In the present study, we show that Cre-dependent recombination in these mice marks multiple neural crest derivatives, including neurons, glia and melanocytes, when … WebbThese mice allow pan-astrocytic, specific and inducible genetic manipulations in vivo for studying astrocyte biology at different developmental stages in neural circuitry/synapses, behavior, disease and injury/trauma. Aldh1l1-Cre/ERT2 BAC transgenic mice are also available on a C57BL/6N-congenic background (Stock No. ... giraffe black and white png

Tamoxifen-inducible glia-specific Cre mice for somatic …

Category:Identity and lineage fate of proteolipid protein 1 gene

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Plp-creert2 mouse

From neural crest cells to melanocytes: cellular plasticity during ...

WebbJoseph et al., 2004), Plp-CreERT2(Leone et al., 2003) and Tyr-CreERT2 (Bosenberg et al., 2006). Genotyping for allCrealleles was performed by ... injected intraperitoneally into the pregnant mother on 1 day for Plp-CreERT2mice at the indicated stages and on 2 consecutive days at E11.5 and E12.5 for Tyr-CreERT2mice. Webb26 juni 2024 · Paper: Tmem119-EGFP and Tmem119-CreERT2 transgenic mice for labeling and manipulating microglia Since Mariko Bennett and Ben Barres published Tmem119 as a marker of microglia distinct from peripheral myeloid cells in 2016, the field has been abuzz with the ability to discern between peripheral immune cells and resident microglia ( …

Plp-creert2 mouse

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Webb南模生物. Language: 中文 . English; 日本語; 한국어; 账户设置; 退出 Webb2 feb. 2006 · Animals. Hemizygous PLP-CreERT2 mice (Leone et al., 2003) and homozygous erbB2 flox mice (Garratt et al., 2000) have been described previously.The erbB2 wt/lacZ mice used in this study carry an allele that encodes a nonfunctional ErbB2-galactosidase fusion protein lacking the tyrosine kinase domain (Britsch et al., …

Webb18 maj 2012 · The characterization of these mouse lines indicates that CreERT2 is essentially functional in osteoclasts. These CtsKCreERT2 transgenic mouse lines …

Webb12 apr. 2024 · In our experiments, we confirmed the high cell specificity of the GLAST-CreERT2 mouse line as extensively described 18. ... e.g. by employing PLP-CreERT2 or … WebbThese mice allow pan-astrocytic, specific and inducible genetic manipulations in vivo for studying astrocyte biology at different developmental stages in neural …

Webb20 aug. 2024 · Plp-CreERT2:Rosa26tdTomato小鼠谱系示踪显示前庭扁平上皮可能来源于支持细胞和移行上皮细胞...

Webb9 dec. 2002 · The CreER T fusion protein translocated to the nucleus and mediated the recombination of a LacZ reporter transgene in myelinating cells of PLP/CreER T mice injected with the synthetic steroid tamoxifen. In untreated animals CreER T remained cytoplasmic, and there was no evidence of recombination. giraffe block toyWebbThe Plp-CreERT2;QkLoxP/LoxP (Qk-Plp-iCKO) mice and littermate controls were injected with tamoxifen at postnatal day 7 and day 8 and their brains were collected at postnatal day 30. Total RNA was extracted by RNeasy Mini Kit and used for sequencing with Illumina HiSeq 2000 Sequencer. Contributor(s) Zhang Q, Zhou X: giraffe blowing bubbleWebbtyrosinekinasedomain(Britschetal.,1998).HemizygousPLP-CreERT2 mice were crossed with erbB2wt/lacZ animals to obtain PLP-CreERT2 erbB2 wt/lacZdoubletransgenicmice.PLP-CreERT2erbB2 animals were then bred with homozygous erbB2flox mice (erbB2flox/flox)toob-taincontrolPLP-CreERT2erbB2wt/flox … fulton county schools start timeWebb18 maj 2012 · The characterization of these mouse lines indicates that CreERT2 is essentially functional in osteoclasts. These CtsKCreERT2 transgenic mouse lines provide a suitable tool to specifically inactivate any loxP-targeted gene in osteoclasts in a spatial and temporal manner. Results and Discussion Targeting construct and validation in cells giraffe blood pressure factWebb30 apr. 2024 · Previously, Delaunay and colleagues 14 used the developing diencephalon as a mouse model and demonstrate that E9.5 Plp1 promoter-expressing cells (labeled by tamoxifen injection to Plp-CreERT2:Rosa26-EYFP reporter mice at E9.5) primarily give rise to neurons in the brain at P0 whereas E13.5 Plp1 promoter-expressing cells exclusively … giraffe blanket throwWebb7 dec. 2024 · CNS degeneration in Cnp-Cre Jab1fl/fl mice is associated with inflammation. Between P40 and P60, in addition to demyelination and neurodegeneration, we observed in Cnp-Cre Jab1fl/fl mice a diffuse microglial/macrophage inflammatory infiltrate, as revealed by anti-IBA1 staining ( Figure 4A ). giraffe black and white outlineWebbUsing a PLP-CreERT2 transgene, we have generated mice that show specific inducible Cre function, as analyzed by cross-breeding experiments into the Rosa26 Cre-LacZ reporter … giraffe blood pressure head