Insulinoma-associated protein 1a

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August undefined, 2024

Nettet21. mai 2024 · Insulinoma-associated-1 (IA-1 or INSM1) is a zinc-finger transcription factor that was identified in a human insulinoma subtraction library, from which it was isolated . Insm1 is an intronless gene encoding a 510-amino acid protein that contains 5 zinc-finger DNA-binding motifs and several potential functional domians ( 2 , 3 ). Nettetinsulinoma-associated 1a Symbol insm1a Nomenclature History Previous Names. zgc:77257; Type protein_coding_gene ... Protein Length Insulinoma-associated protein 1/2 Zinc finger C2H2 superfamily Zinc finger C2H2-type; UniProtKB:F8W3Z6. InterPro 373: UniProtKB:Q6P0F9. InterPro ...

105010943 - Gene ResultLOC105010943 insulinoma-associated protein 1a ...

Nettet29. nov. 2009 · Aims/hypothesis We investigated whether screening for insulinoma-associated protein (IA-2) beta (IA-2β) autoantibodies (IA-2βA) and zinc transporter-8 (ZnT8) autoantibodies (ZnT8A) improves identification of first-degree relatives of type 1 diabetic patients with a high 5-year disease risk, which to date has been based on … Nettet18. mai 2010 · PTHR15065:SF6 INSULINOMA-ASSOCIATED PROTEIN 2 1 hit; PROSITE. View protein in PROSITE; PS00028 ZINC_FINGER_C2H2_1 4 hits; PS50157 ZINC_FINGER_C2H2_2 3 hits; Pfam. View protein in Pfam; PF00096 zf-C2H2 2 hits; … simplicity 1706692sm

103381380 - Gene ResultLOC103381380 insulinoma-associated …

Nettet24. jul. 2024 · Insulinoma is a type of functional neuroendocrine tumor characterized by hypersecretion of insulin, causing hypoglycemia. It typically presents as a solitary benign tumor but can be associated with multiple endocrine neoplasia type 1 (MEN1). … Nettet27. feb. 2024 · The deduced 566-amino acid protein contains an SNAI1/GFI1 motif followed by 2 proline-rich sequences in its N-terminal half and 5 C2H2-type zinc fingers in its C-terminal half. INSM2 shares 51% amino acid identity with INSM1. Northern blot analysis detected a 4.8-kb INSM2 transcript that was highly expressed in heart and … NettetInsulinoma-associated protein 1 (INSM1) is expressed exclusively in embryonic developing neuroendocrine (NE) tissues. INSM1 gene expression is specific for small-cell lung cancer (SCLC), along with achaete-scute homolog-like 1 (ASCL1) and several NE molecules, such as chromogranin A, synaptophysin, … raymarine tactic

Breast cancer with neuroendocrine differentiation: an update …

Insulinoma-Associated Protein 1 Is a Crucial Regulator of ...

NettetUse: Diagnosis of Type 1 Diabetes: The presence of autoantibodies against IA-2 (IA-2A) in patients with diabetes mellitus indicates the presence of autoimmune, type 1 diabetes. Prediction of Type 1 Diabetes: Autoantibodies against IA-2 (IA-2A) in an asymptomatic individual places the subject at increased risk for the development of type 1 diabetes. Nettet23. jan. 2024 · Insulinoma-associated protein 1 (INSM1), a 510–amino acid protein with 5 zinc finger motifs at the carboxyl terminus, is a developmentally regulated transcription factor involved in the development of neuroendocrine differentiation. 1, 2 Its complementary DNA, known as insulinoma-associated 1 (IA-1), was isolated in 1992 … raymarine technical support australiaNettet24. mar. 2004 · IA-2 (insulinoma-associated protein 2), a major autoantigen in type 1 diabetes, is a receptor-tyrosine phosphatase-like protein associated with the membrane of secretory granules of neural and endocrine-specific cells. Loss of IA-2 activity in the … simplicity 1706738

"Nettet7. Borg H, Fernlund P, Sundkvist G, et al. Protein tyrosine phosphatase-like protein IA2-antibodies plus glutamic acid decarboxylase 65 antibodies (GADA) indicates autoimmunity as frequently as islet cell antibodies assay in children with recently diagnosed diabetes mellitus. Clin Chem. 1997 Dec; 43(12):2358-2363. 9439455 " - Insulinoma-associated protein 1a

Insulinoma-associated protein 1a

Characterization of CIMMYT bread wheats for high- and low …

Nettet1. mar. 2024 · Insulinoma‑associated protein 1 (INSM1) is a useful neuro‑ endocrine marker for various neuroendocrine tumours. α‑thalassemia/mental retardation syndrome X‑linked protein (ATRX) and death domain‑associated protein (DAXX) are useful prognostic markers for patients with pancreatic neuroendocrine tumours. However, to … NettetInsulinoma is one of the most common types of tumours arising from the islets of Langerhans cells (pancreatic endocrine tumours). Estimates of malignancy (metastases) range from 5 to 30%. Over 99% of …

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Nettet53626 Ensembl ENSG00000173404 ENSMUSG00000068154 UniProt Q01101 Q63ZV0 RefSeq (mRNA) NM_002196 NM_016889 RefSeq (protein) NP_002187 NP_058585 Location (UCSC) Chr 20: 20.37 – 20.37 Mb Chr 2: 146.06 – 146.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Insulinoma-associated protein 1 is a … NettetLOC106468100 insulinoma-associated protein 1a-like [ (Atlantic horseshoe crab)] Gene ID: 106468100, updated on 4-Feb-2024. Summary Other designations. insulinoma-associated protein 1a-like

NettetInsulinoma-associated-1 (IA-1 or INSM1) encodes a zinc-finger transcription factor, which was isolated from a human insulinoma subtraction library, with specific expression patterns, predominantly in developing neuroendocrine tissues and tumors. INSM1 is key in early pancreatic endocrine, sympatho-a …

NettetLOC105010943 insulinoma-associated protein 1a-like [ (northern pike)] Gene ID: 105010943, updated on 1-Feb-2024. Summary Other designations. insulinoma-associated protein 1a-like ... NettetInsulinoma-associated protein 1 (INSM1) is expressed exclusively in embryonic developing neuroendocrine (NE) tissues. INSM1 gene expression is specific for small-cell lung cancer (SCLC), along with achaete-scute homolog-like 1 (ASCL1) and several NE …

Nettet25. nov. 2024 · Insulinoma-associated 1. A novel marker in Merkel cell carcinoma (cutaneous neuroendocrine carcinoma). J Cutaneous Pathology, 45, 129–135. CrossRef PubMed Google Scholar Tanigawa, M., Nakayama, M., Taira, T., et al. (2024). …

Nettet26. mar. 2024 · Background Insulinoma-associated protein 1 (INSM1), a transcriptional regulator with a zinc-finger DNA-binding domain, has been validated as a cytoplasmic marker for neuroendocrine differentiation of tumor cells. Next to its abundant … simplicity 1705899smNettet2. feb. 2024 · Insulinoma-associated protein 1 (INSM1) is a sensitive and highly specific marker of neuroendocrine differentiation in primary lung neoplasms: an immunohistochemical study of 345 cases, including ... simplicity 1705449smNettetinsulinoma-associated protein 1a: Smed ID: SMED30016266: Length (bp) 1206: Neoblast Clusters. Zeng et. al., 2024 Overview Neoblast Population Sub-lethal Irradiated Surviving X1 and X2 Cell Population . Overview . Single cell RNA-seq of pluripotent neoblasts and its early progenies. simplicity 1707326sm foam sealNettetinsulinoma-associated protein 1a, insulinoma-associated 1-like protein a, zinc finger protein IA-1a. GeneRIFs: Gene References Into Functions. Insm1a-deficient embryos were microphthalmic and displayed defects in rod and cone photoreceptor differentiation; raymarine technical support hotlineNettet1. mar. 2010 · Two hundred and seventy-three CIMMYT bread wheat cultivars and advanced lines grown under irrigated conditions in Mexico during the 2005-06 Yaqui crop cycle were characterized for quality-related genetic traits using gene-specific markers for some high- and low-molecular-weight glutenin subunit (HMW-GS and LMW-GS) genes, … raymarine stuart flhttp://www.cnreagent.com/show1001180/product_93752.html simplicity 1706737NettetInsulinoma-associated-1 (IA-1 or INSM1) encodes a zinc-finger transcription factor, which was isolated from a human insulinoma subtraction library, with specific expression patterns, predominantly in developing neuroendocrine tissues and tumors. INSM1 is … simplicity 1713515sm